Author Archives: Marisa Wexler MS

Study Identifies New Mechanisms of AADC Deficiency Mutations

Mutations discovered in the past five years that cause aromatic amino acid decarboxylase (AADC) deficiency affect the functioning of the AADC protein in previously unappreciated ways, namely promoting aggregation and preventing interactions among AADC protein pairs, a molecular study demonstrates. The new mechanisms identified in the study light the…