The use of real-time magnetic resonance imaging (MRI) during direct-to-brain delivery of gene therapy may help optimize the safety and…
Articles by Lindsey Shapiro, PhD
Researchers have proposed a set of factors for doctors to consider when deciding if a patient is a good fit…
Advanced genetic sequencing enabled the identification of a mutation — deep within a non-protein-coding portion of the DDC gene —…
A unusually mild case of aromatic l-amino acid decarboxylase (AADC) deficiency, one characterized by exercise-induced episodes of involuntary muscle…
Treatment with Upstaza (eladocagene exuparvovec) is estimated to prolong survival and lead to life quality gains for aromatic…
The U.S. Food and Drug Administration (FDA) has launched a pilot program, dubbed START, to accelerate the development of therapies…
About three-quarters of children and adults with aromatic l-amino acid decarboxylase (AADC) deficiency on standard care fail to meet…
Most aromatic l-amino acid decarboxylase (AADC) deficiency patients treated at a center in Taiwan share a common mutation in…
Researchers have gained new insights into the structure of the aromatic amino acid decarboxylase (AADC) enzyme — which is faulty…
GenScript ProBio and Comprehensive Cell Solutions (CCS) are partnering to accelerate the development of new cell and gene…